Highly Sensitive and Selective Detection of Melatonin in Biofluids by Antipyrine Based Fluorophore

Sathya, Vijayakumar and Srinivasadesikan, Venkatesan and Ming‑Chang, Lin and · Padmini, Vediappen (2023) Highly Sensitive and Selective Detection of Melatonin in Biofluids by Antipyrine Based Fluorophore. Journal of Fluorescence volume. pp. 383-392. ISSN 1053-0509

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School: School of Applied Science and Humanities > Department of Chemistry

Department: School of Applied Science and Humanities > Department of Chemistry

Abstract

Abstract
A simple fuorescent based organic fuorophore was synthesized and it shows signifcant fuorescent intensity with melatonin
(MLN). Hence, it was applicable to the detection of MLN by colorimetric and fuorimetric techniques at neutral pH. Under
optimized experimental condition, the synthesized organic fuorophore detects MLN selectively in the presence of other
interfering biomolecules through ICT mechanism. The melatonin sensing mechanism is supported by DFT and 1
H-NMR titration. Based on the fndings, this method can be applied to design a simple clinical diagnostic tool for MLN.

Item Type:	Article
Subjects:	AC Rearch Cluster
Depositing User:	Unnamed user with email techsupport@mosys.org
Date Deposited:	06 Nov 2023 06:50
Last Modified:	06 Nov 2023 06:50
URI:	https://ir.vignan.ac.in/id/eprint/321

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