Development of optical biosensor for the detection of glutamine in human biofluids using merocyanine dye

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Vijayakumar, Sathya and Appadurai, Deepa and Lakshmi Kandhan, Sangeetha and Venkatesan, Srinivasadesikan and Shyi-Long, Lee and Vediappen, Padmini (2022) Development of optical biosensor for the detection of glutamine in human biofluids using merocyanine dye. Journal of Fluorescence, 32. pp. 1389-1396. ISSN 1053-0509

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School: School of Applied Science and Humanities > Department of Chemistry

Department: School of Applied Science and Humanities > Department of Chemistry

Abstract

Abstract
Merocyanine dye based fuorescent organic compound has been synthesized for the detection of glutamine. The probe showed
remarkable fuorescent intensity with glutamine through ICT (Intermolecular Charge Transfer Mechanism). Hence, it is
tested for the detection of glutamine using colorimetric and fuorimetric techniques in physiological and neutral pH (7.2).
Under optimized experimental conditions, the probe detects glutamine selectively among other interfering biomolecules.
The probe has showed a LOD (lower limit of detection) of 9.6× 10–8 mol/L at the linear range 0–180 µM towards glutamine.
The practical application of the probe is successfully tested in human biofuids

Item Type:	Article
Subjects:	AC Rearch Cluster
Depositing User:	Unnamed user with email techsupport@mosys.org
Date Deposited:	06 Nov 2023 06:44
Last Modified:	06 Nov 2023 06:44
URI:	https://ir.vignan.ac.in/id/eprint/319

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