A Prospective Review on Novel Strategies for Preparation and Evaluation of Nanosponge Tablets

Nanosponges are small sponges where they reach the target site and stick to that surface and initiate to release in a controlled manner they can also be loaded with the various types of medications. Drugs loaded with Nanosponges improves their dissolution rate, solubility, rate of release, stability, reduces the frequency of dosing and improves bioavailability. Nanosponges are mostly used in targeted drug delivery system. Drug delivery is the major problem faced in the pharmaceutical field from a long time by the invention of Nanosponge technology has become important step so that we can minimize some problems like poor solubility, poor stability and dosing frequency. The main advantage of this Nanosponge is it can be loaded by both hydrophilic and lipophilic drugs. The present review article is todiscuss about the general introduction, composition of Nanosponges, drugs loaded withNanosponges, different preparation techniques and evaluations methods for the Nanosponge tablets. Zeta potential, Fourier transform-infrared spectroscopy, determination of percentage yield, particle size analysis, porosity, invitro dissolution studies and entrapment efficiency by these characterizations we can know the inclusion complexes formed in between drug and Nanosponges, mainly lansoprazole loaded Nanosponges characterization parameters and evaluations are presented in this article. Nanosponges can deliver the drug through various routes like oral, topical, aerosol and parenteral administration.